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Maximum effect on A1C is generally seen by 2440 weeks

Acknowledgements We thank Umut Erhan, Azadeh Houshman-regaard and Anders Strathe of Novo Nordisk A/S (Denmark) and Zu Ning of Novo Nordisk China A/S (China) for their contributions to the manuscript

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While significant adverse effects on liver function haven't been widely reported in initial studies, it's a critical area for ongoing scrutiny

By week 6 of treatment, the majority report significant improvement or complete resolution

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